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DIPLOMA PART - II
LIST OF PRACTICAL :
(A) Introduction to experimental Pharmacology :
1.
Preparation of different solutions for experiment.
2. To study common
laboratory animals and anesthetic used in animal study.
3. To study
commonly used instrument in experimental pharmacology.
4. To study some
common and standard techniques used for administration of drugs.
(B) Pharmacology of cardiovascular system. (Computer software may be used as substitute) :
1.
Effect of K+, Ca++, acetylcholine, adrenaline on frog heart.
2. To study the
effect of Ach on rectus abdominus muscle of frog.
3. To study the
effect of Spsmogens and relaxants on rabbit's intestine.
(C) Only demonstrations or using computer software :
1.
To study the effect of local anesthetics on rabbit cornea.
2. To study the
effect of mydritiacs and meiosis on rabbit eye.
3. To study the
action of strychnine on frog.
4. To study the
effect of digitalis on frog heart.
5. To study the
effect of hypnotics on mice
6. To study the
test for pyrogens
7. To study the
taming & hypnosis potentiating effect of chlorpromazine on mice or rats.
8. To study the
effect of convulsions and anti convulsions effects on mice or rat.
9. To study the
effect of analgesics on rat.
Theory :
1. Bio-statistics : [14]
a) Basic concepts of
Statistics : Data, Data Graphic, frequency distribution measures of central
tendency
(Mean, Median, Mode, Harmonic
mean, Geometric mean and scattering of data (Range, Mean,
deviation, Standard deviation,
SEM Applications in Pharmaceutical Validation).
b) Introduction to probabilities : Binomial and
Normal probabilities distribution.
c) Sample and sampling method : Sample size and
its significance. Sampling techniques and their
application in pharmacy.
d) Hypothesis testing (t-statistics (application
in dissolution testing of solid dasage forms).
e) Correlation analysis, Correlation coefficient,
Spearman's rank correlation coefficient.
f) Linear regression analysis (applications
in Beer's Lamberts Curve, stability study, introduction to curve
fitting
techniques.
2. Computer : [58]
a) Introduction to
computers-Introduction to i/o devices, storage devices, binary conversion,
computer
classification, applications of
computers in pharmacy.
b) Introduction to DOS commands : File Name and
different extensions, Internal and External Commands.
Introduction to Windows.
Use of Menu bar, Taskbar, Desktop, My Computer, Control Panel,
Windows
Explorer, Neighborhood,
Recycle Bin.
c) MS EXCEL preparation of templates for
application in pharmaceutical chemistry, pharmaceutical
technology,
pharmacology and pharmacognosy for example statistical treatment of data
for Beer's
Lamberts curve, solution of
problems based on physical chemistry, pharmaceutical engineering,
stability
study area under the curve. Rf
value and other elementary problems of pharmaceutical importance.
Special
attention must be given to arithmetic expressions. Hierarchy of operation,
library function such as
logarithm, square root, standard
deviation, sum, average, t-test. Drawing graphs in EXCEL line graph,
histogram, pie chart. At least one
graph for each discipline of chemistry, pharmaceutical technology,
pharmacology and pharmacognosy -
Editing chart features such as formatting charts, adding legends and
changing data.
d) Word Processing MS WORD - 97 :
Word
Essentials, Typing and Editing, Finding and Replacing, Auto correct and Auto text-Reusing
Text
and Graphics, Formatting Text,
Formatting Paragraphs, Formatting and Sorting Lists, Page Design and
Layout, Page Setup : Margins, Page
Numbers and Other Items, Spell Check and Grammar Use of
Thesaurus, Newspaper - style Columns,
Working with Tables.
e) Introduction to E-Mail and internet-demonstration of sites
of pharmaceutical interest.
f) BASIC language - Elementary programming in BASIC
language - Algorithm flow chart. Solution of
problems based on biostatistics and other
simple problems of pharmaceutical interest.
Basics, Constants &
Variables, expressions, printer controls, Jumping, Branching and Looping and
subscripted Variables (sorting)
Practical :
Practicals based on the topics covered in theory MS-EXCEL Stress must be given to topics of pharmaceutical interest only (e.g. statistical analysis of pharmaceutical data, stability study, area under the curve, calculation of molecular weight, calculation of solubility, buffers, filtration, acid-base titration, oxidation reduction, physical pharmaceutics, pharmaceutical engineering, etc.)
Practicals based on pharmaceutical applications of students and paired t-test-SD-SEM. Chi-square test - ANOVA regression analysis (application to stability testing) ANOVA (application in pharmacokinetics.)
Assignment : Computerization of any two practicals taught in first B.Pharm. (text, tables, figures, calculation steps, etc.)
Book Recommended :
1. Pharmaceutical Statistics - S.Botton
2. MS-Office - APTECH, TMH Publications
3. Working in Microsoft Office by RON MANSFIELD
4. MS-Office Taxali
5. PC for Window made simple
6. Basic Programming by E.Balaguruswamy
7. Basic Programming by V.K.Jain
